Magnolia Officinal Bark Extract is a major constituent of currently marketed dietary supplements, cosmetic and toothpaste products, and the main components are Magnolol and Honokiol. It has antibacterial, anti-inflammation, antioxidant and anti- depressed effects. The Magnolol has significant antimicrobial activities against Gram-positive bacteria and acid-resistant bacteria and also has significant anti-caries effect.
Magnolia Officinal Bark Extract is a major constituent of currently marketed dietary supplements, cosmetic and toothpaste products, and the main components are Magnolol and Honokiol. It has antibacterial, anti-inflammation, antioxidant and anti- depressed effects. The Magnolol has significant antimicrobial activities against Gram-positive bacteria and acid-resistant bacteria and also has significant anti-caries effect.
Magnolia officinalis (commonly called houpu magnolia or magnolia-bark) is a species of Magnolia native to the mountains and valleys of China at altitudes of 300–1500 m. Today, the bulk of bark used for commercial and domestic use is supplied by plants in cultivation.
It is a deciduous tree growing to 20 m in height. The bark is thick and brown, but does not fissure. The leaves are broad, ovate, 20–40 cm long, and 11–20 cm broad. The flowers are fragrant and 10–15 cm wide, with 9–12 (rarely to 17) white tepals, and appear from May to June.
The highly aromatic bark is stripped from the stems, branches, and roots and used in traditional Chinese medicine, where it is known as hou po (厚朴; thus the common name). The traditional use indications are to eliminate damp and phlegm, and relieve distension.
The bark contains magnolol and honokiol, two polyphenolic compounds that have been demonstrated as peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists and GABAA modulators. Preclinical studies have evaluated their various potential applications including antioxidant, anti-inflammatory, antitumor, and antimicrobial properties.
